NEWS

​​

11/24

Happy to share our latest publication in Nature Commun. with you! Thanks to all co-authors for your support!​

https://rdcu.be/d0I79

​

08/23

​

New publication in PNAS online! Thanks for a fantastic collaboration, Xianping Dong (Dalhousie University, Canada)!

Thanks Dawid and Eva for your valuable contributions!

​

https://pubmed.ncbi.nlm.nih.gov/37585464/

​​

04/23

​

Now also find us on ion channel labs world map via

​

https://www.ionchannellibrary.com/ion-channel-world-map/#

​

https://www.linkedin.com/company/ionchannellibrary/

​​

02/23

Endolysosomal TPCs regulate social behavior by controlling oxytocin secretion

​

https://www.pnas.org/doi/10.1073/pnas.2213682120

​

Congratulations Lora et al!

​

09/22

​

Congratulations Monther Abu-Remaileh to your new paper in Nature about CLN3. Thanks that we could contribute to this work!

​

https://www.nature.com/articles/s41586-022-05221-y

​

08/22

​

Congratulations and thank you to all who have contributed to our latest paper in EMBO Mol Med. Great team work!

​

https://www.lmu.de/en/newsroom/news-overview/news/ion-channel-as-possible-target-structure-for-therapies.html

​

​

07/22 Lab event: hike from Tegernsee to Schliersee!

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

07/22

​

Congratulations Eva Maria Weiden! Winner of iPAD for second best poster at GRK meeting in Herrsching, Ammersee! (left to right: Eva Maria Weiden, Lena Schaller, Prof Dr Thomas Gudermann, GRK speaker)

 

 

 

 

 

 

 

 

 

 

 

 

​

​

​

​

​

​

​

 

06/22

​

Nature Commun. paper "Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes" accepted!

​

Congratulations Dawid, Anna, Carla, Eva!

Thanks Sandip Patel (UCL) for great collaboration!

​

​

​

​

06/22

​

Congratulations Dr. Julia Böck, PhD!

​

​

​

04/22

​

Congratulations Dr. Barbara Spix, PhD!

​

​

​

​

​

​

​

 

​

02/22

​

Congratulations Dr. Einar Krogsaeter, PhD!

​

https://www.linkedin.com/feed/update/urn:li:activity:6902120166415593472/

​

01/22

​

Nature Commun. paper "Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice" online!

​

Congratulations Barbara et al.!

https://www.nature.com/articles/s41467-021-27860-x

​

https://www.lmu.de/en/newsroom/news-overview/news/copd-ion-channel-regulates-molecule-that-contributes-to-disease.html
https://www.cup.uni-muenchen.de/en/events-and-news/archive/2022/copd-ion-channel-regulates-molecule-that-contributes-to-disease/?lang=default

https://www.cup.uni-muenchen.de/de/aktuelles/archiv/2022/copd-ionenkanal-reguliert-krankheitsfoerderndes-molekuel/
https://www.lmu.de/de/newsroom/newsuebersicht/news/copd-ionenkanal-reguliert-krankheitsfoerderndes-molekuel.html

 

​

​

10/21 Nobel Prize for TRP channels! A big step for our field of reserach!

​

https://www.nobelprize.org/prizes/medicine/2021/press-release/

​

​

​

​

​

​

​

​

08/21 New paper in EMBO Mol. Med. online

https://pubmed.ncbi.nlm.nih.gov/34411438/

​

02/21 New paper in Cell Chem Biol online! (novel antagonists for TPCs)

https://pubmed.ncbi.nlm.nih.gov/33626324/

​

12/20-11/21

 

 

​

​

​

​

​

​

​

​

​

​

https://www.mdpi.com/journal/cells/special_issues/Organellar_Ion_Channels_and_Transport_Proteins_in_Health_and_Disease

If you wanna contribute please email us!

​

https://www.mdpi.com/journal/cells/special_issues/Organellar_Ion_Channels_and_Transport_Proteins_in_Health_and_Disease

If you wanna contribute please email us!

​

11/20 Science Advances paper online! Congratulations again to the first authors Cheng-Chang and Einar!

Chen C-C, Krogsaeter E, Butz E, Li Y, Puertollano R, Wahl-Schott C, Biel M, Grimm C#: TRPML2 is an osmo-/mechano-sensitive cation channel in endolysosomal organelles.

​

https://advances.sciencemag.org/content/6/46/eabb5064

​

See also:

https://www.en.uni-muenchen.de/news/newsarchiv/2020/grimm_mechanosensitivity.html
https://www.uni-muenchen.de/forschung/news/2020/grimm_mechanosensitivitaet.html

​

09/20 Science Advances paper in press! Congratulations to the first authors Cheng-Chang and Einar!

Chen C-C, Krogsaeter E, Butz E, Li Y, Puertollano R, Wahl-Schott C, Biel M, Grimm C#: TRPML2 is an osmo-/mechano-sensitive cation channel in endolysosomal organelles. Science Adv in press

​

03/20 eLIFE paper "Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function" online!

https://elifesciences.org/articles/54712

Congratulations Susanne, Yu-Kai, Anna, Einar!

Article recommended by F1000:

https://f1000.com/prime/737547365

 

03/20 New review in Frontiers in Immunology online: TRPML Cation Channels in Inflammation and Immunity

https://www.frontiersin.org/articles/10.3389/fimmu.2020.00225/full

Congratulations Barbara, Yu-Kai and Carla!

​

01/20 New DFG (German Research Council) Grant GR-4315/4-1 on two-pore channel agonist characterization accepted!

​

12/19 Nature Commun. paper "TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway" online

https://www.ncbi.nlm.nih.gov/pubmed/31822666

Congratulations Anna!

​

08/19 Christian Grimm speaking at Gordon Research Conference on Organellar Transporters and Channels in West Dover, Vermont, USA

https://www.grc.org/organellar-channels-and-transporters-conference/2019/

​

07/19 Welcome Ya-Ching Chang from Taiwan (Summer Intern)!

​

06/19 Congratulations to Dr. Yu-Kai Chao! Well deserved PhD title!

​

05/19 Dr. Anna Scotto-Rosato (TIGEM, Italy) back in the lab financed by the MLIV Foundation, USA. Welcome back Anna!

 

05/19 NCL Foundation fellowship for Einar Krogsaeter granted. Congratulations Einar!

​

​

​

​

​

​

​

​

​

​

​

​

 

​

​

​

​

​

​

​

​

​

​

​

05/19 Ponsawan Netcharoensirisuk starting as DAAD/TRF financed visiting PhD student in the lab. Welcome Ponsawan!

​

04/19 Carla Abrahamian starting as a new PhD Student in the lab. Welcome Carla!

​

03/19 Christian Grimm, Yu-Kai Chao, and Cheng-Chang Chen visiting Sui-Yuan Chang at NTU Taipeh, Taiwan

(funded by DAAD)

​

03/19 Christian Grimm speaking at Gordon Research Conference on Lysosomal Diseases in Galveston, USA

https://www.grc.org/lysosomal-diseases-conference/2019/

​

02/19 Marcel Passon starting as a new MA Student in the lab. Welcome Marcel!

​

01/19 Nature Commun. paper "Remodeling of secretory lysosomes during education tunes functional potential in NK cells" online

https://www.ncbi.nlm.nih.gov/pubmed/30705279

​

11/18 EMBO J. paper "A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease" online.

Congratulations Yu-Kai!

https://www.ncbi.nlm.nih.gov/pubmed/30498130

​

11/18 BBA Review "The protein interaction networks of mucolipins and two-pore channels" online. Congratulations Einar!

https://www.sciencedirect.com/science/article/pii/S0167488918304919

​

11/18 eLIFE paper "Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells" online

https://elifesciences.org/articles/39720

See also comment in eLIFE by Prof. Dr. Antony Galione

https://www.ncbi.nlm.nih.gov/pubmed/30499445

Article highlighted by Erin R. Williams in Sci. Signal. 18 Dec 2018: Vol. 11, Issue 561, eaau2215:

http://stke.sciencemag.org/content/11/561/eaau2215.full

​

11/18 Julia Böck starting as a new PhD Student in the lab. Welcome Julia!

​

11/18 Start of the new lab at the Department of Pharmacology and Toxicology, University of Munich (LMU) Medical Faculty, Nussbaumstr. 26, 80336 München